TGEN OCNDS Research Program

TGEN Foundation

TGen, the Translational Genomics Research Institute, is an Arizona-based, nonprofit medical research institute dedicated to conducting groundbreaking research with life-changing results. TGen’s areas of research include cancer, diabetes, neurological disorders and infectious diseases. TGen physicians and scientists work to unravel the genetic components of both common and rare complex diseases in adults and children through the efficiency and effectiveness of translational research (the process of rapidly moving research towards patient benefit). . The Translational Genomics Research Institute’s (TGen) Center for Rare Childhood Disorders (C4RCD) is located in Phoenix, AZ and led by Matt Huentelman, Ph.D., Vinodh Narayan, MD and Keri Ramsey, BSN. TGen joined the City of Hope system in November 2016. City of Hope provides a significant clinical setting to advance scientific discoveries made by TGen.


By partnering with TGen, we are helping children who do not have access to genetic testing. Families are not charged for care and genetic testing at TGen. Access to health care and social determinates are enormous hurdles to receiving a diagnosis. Whether it is access to health insurance to pay for testing or getting time off work to go to doctor appointments or traveling long distances for care, there are many obstacles impeding families’ ability to receive a diagnosis. For undiagnosed families and children, TGen is their last hope in their diagnostic odyssey which spans many years and countless visits to doctors and specialists.


With our donors' support, in 2019, we established the CSNK2A1 Foundation Research Program at TGen. Currently, TGen is conducting high throughput drug screening on zebrafish to determine promising already approved FDA drug compounds which will then be tested on the patient-derived iPSC cells in preparation for a clinical trial.

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